Skip to main content

Lilly says Taltz superior to Humira in late-stage psoriatic arthritis trial

By Tamara Mathias
(Reuters) - Eli Lilly and Co said on Monday its psoriatic arthritis drug, Taltz, was found to be more effective than the world's best-selling prescription medicine, AbbVie Inc's Humira, in a late-stage trial.
The trial was the first of its kind to test Taltz and the standard-of-care, Humira, head-to-head in patients with active psoriatic arthritis, a form of arthritis that affects some people who have psoriasis.
The study showed Taltz was as effective as Humira in improving the symptoms of psoriatic arthritis, as measured by achieving a reduction in disease activity of at least 50 percent, compared with patients that showed such results on Humira after 24 weeks.
However, the drug was found superior to Humira in clearing skin completely in a greater number of patients and achieving both results simultaneously, Lilly said.
"This is a very, very high hurdle to meet and gives doctors confidence that they can prescribe Taltz as a treatment for newly diagnosed patients. It treats joints as well as provides the added value of clearing skin," Lotus Mallbris, vice president of immunology development at Lilly, told Reuters.
Lilly's Taltz was first approved in the United States in 2016 for treating plaque psoriasis and had total revenue of about $560 million in 2017. The Indianapolis-based drugmaker said it planned to present detailed data from the study in 2019.
Humira has been the top-earner for AbbVie since the company was spun off from medical device maker Abbott Labs more than five years ago. Last year, the drug brought in worldwide sales of $18 billion, accounting for about two-thirds of AbbVie's net revenue.
However, Humira's sales are expected to come under pressure with a number of biosimilar versions set to hit the market.
(Reporting by Tamara Mathias and Aakash Jagadeesh Babu in Bengaluru; Editing by Anil D'Silva)


Popular posts from this blog

Lyon vs Barcelona: Lionel Messi and teammates get important draw in France

- Lyon vs Barcelona game in the Champions League round of 16 tie ended goalless on Tuesday night, February 19 - Goalkeeper Anthony Lopes of Lyon was superb for his club as he denied the likes of Lionel Messi and Dembele - Barcelona will have the chance in the second leg playing in front of their fans at the Camp Nou Lyon were on Tuesday night, February 19, forced to a goalless draw by visiting Spanish giants Barcelona in the first leg of their Champions League round of 16 encounter. The French club have never beaten the Catalan giants in their history, and Lyon players wanted to break this record, but Barcelona proved an hard nut for them to crack. Barcelona got the first chance of the game in the 5th minute when Gerard Pique sent a long ball to Dembele who was in a good position, but he failed to utilize the opportunity. Lionel Messi and Suarez also combined well three minutes later to beat Lyon defense, but goalkeeper Anthony Lopes was brilliant to deny them. Lyon's got their b…

Plateau governorship election is inconclusive - INEC

- Pateau state governorship election has been declared inconclusive - The commission said the total number of votes cancelled is more than the difference in the number of votes the two major candidates got - The total number of votes cancelled in the state is 49, 347, while the total margin between leading candidates is 44, 929 The Independent National Electoral Commission (INEC) on Monday, March 11, declared the governorship elections in Plateau state inconclusive. Professor Richard Kimbir, the Returning Officer for the election in the state announced this on Monday in Jos, after collating results from the 17 local government areas of the state, the News Agency of Nigeria (NAN) reports. Kimbir, who is the Vice Chancellor of Federal University of Agriculture, Makurdi, said the total number of votes cancelled is more than the difference in the number of votes the two major candidates got, “hence was constrained to declare the polls inconclusive”. The returning officer said Simon Lalon…

Fulham vs Chelsea: Jorginho's goal gives the Blues a 2-1 win at Craven Cottage

Fulham vs Chelsea's Premier League game ended 2-1 in favor of the Blues at Craven Cottage - Gonzalo Higuain and Jorginho scored for Chelsea, while Calum Chambers netted for Fulham - Chelsea are still occupying sixth position on the Premier League standings with 56 points Fulham's unimpressive performance this season in the Premier League continued on Sunday, March 3, as they were beaten by Chelsea 2-1 at Craven Cottage. After sacking manager Claudio Ranieri, fans were of the hope that the players would redeem themselves by beating visiting Chelsea, but they could not. Chelsea also went into this game with the target of getting the maximum three points so as to restore their hopes of fighting for the top four teams in the Premier League. There were mutiny among Chelsea fans before the start of the match as some were livid with the decision of Maurizio Sarri to start goalkeeper Kepa Arrizabalaga. Maurizio Sarri's men took the lead in the 20th minute through Gonzalo Higuain…